---

1. Reversible uncompetitive enzyme inhibition occurs when the inhibitor binds to

A. enzyme-substrate complex (ES) only B. free enzyme at substrate binding site C. enzyme at a site different from substrate binding site D. enzyme-substrate complex but at a site different from substrate binding site

---

2. The observations of study of hydrolysis of a drug in an aqueous solution were plotted as a logarithm of the amount of drug remaining (on Y-axis) against time (on X-axis) and was found to be linear. What might be the correct inference

A. The reaction is zero-order B. The slope is 2.303/k. C. The units of k are concentration-1 time-1. D. The half-life is t1/2 = 0.693/k.

---

3. Attention deficit hyperactivity disorder (ADHD) may be treated with behavior management, educational programs, parental counseling and medications. Which of the following medications is NOT generally used in the treatment of ADHD in children

A. methylphenidate B. dexamphetamine C. imipramine D. clonazepam

---

4. Who is Health Minister in Govt. of India (Health &Family Welfare Department)

A. Smriti Irani B. Dr. Harsh Vardhan C. Shri Sanjeeva Kumar D. Rajesh Tope

---

5. Phototoxicity shown by all EXCEPT

A. Doxycycline B. Chlorpromazine C. Thiazide and quinolones D. Rosiglitazone

---

6. Phenolphthalein is used as indicator in acid base titration because it shows colors as

A. pH less than 1, orange. B. pH 0-8, and above 13 colorless. C. pH-8-13 pink D. All of the above

---

7. The optimal pH range for the Karl Fischer reaction to occur with Karl Fischer reagent is

A. 2 to 6 B. 5 to 8 C. 8 to 12 D. 12 to 14

---

8. Ketone on reduction gives

A. Primary alcohol B. Secondary alcohol C. Aldehyde D. Carboxylic acid

---

9. Which of the following functional groups is likely to be present in a molecule that has peaks in the infrared spectrum at 1000-1250 cm-1(strong), but does not have peaks at 3200-365 or 1630-1820cm-1

A. Alcohol B. Aldehyde or ketone C. Ether D. Ester

---

10. Which is India's first public sector enterprise

A. Air-India B. Indian Telephone Industries (ITI) C. Bharat Sanchar Nigam Limited (BSNL) D. Oil and Natural Gas Corporation

---

11. The term that describes spreading of cancer is

A. Malignancy B. Invasiveness C. Metastasis D. Microstasis

---

12. Which is not used in treatment of asthma

A. Budesonide B. Isoniazid C. Cromolyn sodium D. Zafirlukast

---

13. Aluminium tertairy butoxide in ethanol as solvent is used in

A. Oppenaur oxidation B. Clemmensens reduction C. MPV reduction D. Wolf Kishner reduction

---

14. Calcium channel blockers can be divided into three classes based on their chemical structure. Which of the following is not a class of calcium channel blockers

A. Aryloxyethanolamine B. Phenylalkylamines C. Dihydropyridines D. Benzothiazepines

---

15. When granules stick to die what may be a remedy

A. External lubrication B. Drying of granules C. Decrease the dwell time D. Increase in binder quantity

---

16. New education system envisages the education system of pattern

A. 5 + 5 + 2 B. 5 + 3 + 3 + 4 C. 10 + 2 + 3 D. 10 + 2 + 4

---

17. Under what reaction conditions does the electrophilic chlorination of aromatic compounds usually occur

A. NaCl, CH3OH B. Cl2AICl3 C. Cl2CCl4 D. NaCl, EtOH

---

18. Which of the following is the strongest activating group in electrophilic aromatic substitution reactions

A. -OCH3 B. -N(CH3)2 C. -CO2CH3 D. -NO2

---

19. Which of the following compounds has the most signals in the noise-decoupled 13C NMR spectrum

A. o-dibromobenzene B. m-dibromobenzene C. p-dibromobenzene D. 1,3,5-tribromobenzene

---

20. Antipsychotic drugs work by blocking post-synaptic dopamine __ receptors, particularly in the mesolimbic-mesocortical pathway

A. D4 B. D5 C. D2 D. D1