NIPER-JEE PYQ 2020
QUIZ NO 6
TOTAL QUESTIONS = 20
1. Who has been appointed as the head of the committee formed by the government to address the issues of drug security in the country in the context of Novel Corona virus outbreak
A. Vashishtha Narayan Singh
B. Gita Mittal
C. R.K. Mathur
D. Eswara Reddy
2. Recently ranitidine, metformin were in news due to presence of which impurity
A. Nitrosodimethylamine
B. Methylnitrile
C. Diethylene glycol
D. 4-aminobiphenyl
3. Fries rearrangement reaction of phenol ester leads to the formation which type of product
A. Alkene
B. Aldehyde
C. Alcohol
D. Ketone
4. In which medium Favorskii rearrangement does occur
A. Neutral
B. Acidic
C. Basic
D. Amhiprotic
5. Glycine and proline are the most abundant amino acids in the structure of
A. Hemoglobin
B. Myoglobin
C. Insulin
D. Collagen
6. Which of the following is an opioid-like agonist
A. Phenobarbital
B. Diltiazem
C. Pemoline
D. Propoxyphene
7. Which of the following compounds will not absorb UV radiations
A. Chloral hydrate
B. Salicylic acid
C. Acetanalide
D. Chloramphenicol
8. Which of the following is not aromatic
A. Thiophene
B. Dioxane
C. Pyrrole
D. Isoxazole
9. Alcohol and carboxylic acid in presence of dehydrating agent gives which compounds
A. Amides
B. Esters
C. β-hydroxyketone
D. Anhydride
10. Considering 'fluid mosaic model' of cell membrane, which one of the following statements is CORRECT with respect to the movement of lipids and proteins from one lipid monolayer to the other i.e. flip-flop movement
A. Neither lipids, nor proteins can flip-flop
B. Both lipids and proteins can flip-flop
C. While lipids can rarely flip-tlop, proteins can not
D. While proteins can flip-flop, lipids can not
11. How many chiral centers are present in one molecule of camphor
A. 0
B. 1
C. 2
D. 3
12. Cilostazol, a drug used in the treatment of intermittent claudication, inhibits which phosphodiesterase enzyme for its clinical effect
A. PDE3
B. PDE4
C. PDE5
D. PDE6
13. Which of the following antiplatelet drugs is a reversible inhibitor of ADP receptors
A. Clopidogrel
B. Prasugrel
C. Ticagrelor
D. All of the above
14. The most essential fatty acid is
A. Linolenic acid
B. Oleic acid
C. Arachidonic acid
D. Palmitic acid
15. Ticlopidine acts as
A. antagonist of P2Y12 receptor
B. agonist of P2Y12 receptor
C. agonist of GPIB/lIA receptor
D. antagonist of GPIIB/|IA receptor
16. Carbonyl group can be reduced to alkane with the help of catalyst
A. H2N-NH2, KOH, heat
B. Zn/Hg HCI
C. LiAIH4
D. P, Q and R
17. When the velocity of enzyme activity is plotted against substrate concentration, which of the following is obtained
A. Parabola
B. Hyperbolic Curve
C. Straight line with positive slope
D. Straight line with negative slope
18. The active site of chymotrypsin consists of a catalytic triad of which of the following amino acid residues
A. Serine, histidine and glutamate
B. Threonine, histidine and aspartate
C. Serine, histidine and aspartate
D. Methionine, histidine and aspartate
19. Which of the following types of lipid aggregates has maximum stability
A. Micelles
B. Bilayer
C. Liposome
D. Myelin sheath
20. Which of the following is choline containing lipid
A. Phosphatidylserine
B. Phosphatidylglycerol
C. Phosphatidylethanolamine
D. Sphingomyelin
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