NIPER-JEE PYQ 2020
QUIZ NO 2
TOTAL QUESTIONS = 20
1. Arrange in the order of increasing basicity piperidine, pyrrole, pyrimidine, morpholine
A. Piperidine> pyrrole> pyrimidine> morpholine
B. Pyrrole> piperidine> morpholine> pyrimidine
C. Pyrimidine> piperidine> morpholine> pyrrole
D. Piperidine> morpholine> pyrimidine> pyrrole
2. Which of the following diseases is NOT associated with corona virus
A. SARS-CoV-1
B. MERS
C. COVID-19
D. Swine flu
3. IUPAC of carbamazepine is
A. 5H-dibenzo[b,e]azepine-5-carboxamide
B. 5H-dibenzo[b,f]azepine-5-carboxamide
C. 5H-dibenzo[b.g]oxepine-5-carboxamide
D. 5H-dibenzo[b,d]azepine-5-carboxamide
4. Which of the following alkaloids is derived from tyrosine
A. Quinine
B. Morphine
C. Atropine
D. Vinca alkaloid
5. Carvedilol is a mixture of how many enantiomers
A. 2
B. 4
C. 6
D. 8
6. Why is DSS used instead of TMS as the 1H chemical shift reference for a biological sample
A. TMS can denature proteins
B. The chemical shift of TMS is dependent on temperature
C. DSS has a higher solubility in aqueous solution
D. DSS is widely used in protein sample preparation
7. Which international clinical trial is launched by WHO and partners to help find an effective treatment for COVID-19
A. Solidarity
B. Dissidence
C. Severance
D. Dissension
8. Lupron implant is an example of
A. Erodible implant
B. Implant pump
C. Both (A) and (B)
D. None of these
9. Full form of COVID-19 is
A. Co-viral disease-19
B. Corona virus disorder-19
C. Corona Virus disease-19
D. Corona Virus deficiency syndrome-19
10. For maximum bioavailability, drug should be targeted at
A. Stomach
B. Small intestine
C. Large intestine
D. Colon
11. Which of the following virus is not named on the basis of geographical location
A. MERS and Ebola
B. Zika and West Nile virus
C. Marburg
D. Rubella
12. Hand-foot syndrome (palmar-plantar erythrodysesthesia) is NOT caused by
A. 5-fluorouracil
B. capecitabine
C. mitomycin
D. doxorubicin
13. Cimetidine acts by blocking
A. Na-H-ATPase
B. Na-K ATPase
C. H2 receptor
D. H1 receptor
14. Nerve gases used as warfare agent is/are
A. SARIN
B. TABUN
C. SOMAN
D. All of the above
15. One letter symbol of Arginine is
A. K
B. A
C. R
D. D
16. First Indian pharma company
A. Alembic Chemical Works
B. Bengal Chemicals and Pharmaceuticals
C. Cipla
D. Dabur India Ltd
17. For a drug following linear pharmacokinetics what would be the change in tmax if the oral dose of the drug is doubled
A. tmax remains unchanged
B. tmax doubled max
C. tmax decreased to half
D. Can not be predicted
18. Which isomer(s) of xylene will exhibit 3 peaks in the 13C NMR spectrum
A. 0-xylene
B. m-xylene
C. p-xylene
D. All of the above
19. Which of the following drug transport mechanism across the cell membrane is bidirectional in nature
A. Passive diffusion
B. Active transport
C. Pinocytosis
D. Facilitated diffusion
20. A thermodynamically-controlled reaction will yield predominantly the
A. product whose formation requires the smallest free energy of activation.
B. more/most stable product
C. product that can be formed in the fewest steps.
D. product that is formed at the fastest rate.
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