NIPER PYQ 2019
QUIZ NO 3
TOTAL QUESTIONS = 20
1. For a generic drug to be bioequivalent to an innovator drug (per FDA), it must be measured in ––––––– of subjects to fall within ¬¬¬–––––– of the mean of the test population bioavailability
A. 50,50
B. 80,20
C. 20,80
D. 95,5
2. Drave's test used for evaluation of
A. Wetting agent
B. Disintegrant
C. Binder
D. Lubricant
3. New Drug Application is done
A. Between preclinical studies and Phase I
B. After Phase I
C. After phase II
D. After phase III
4. Aniline is synthesized by
A. Zinin reaction and Bechamp reduction
B. Cumene process and Coal pyrolysis
C. Kolbe-Schmitt reaction
D. Wurtz-Fittig reaction
5. The Wittig reaction or Wittig olefination is a chemical reaction of an aldehyde or ketone with
A. a triphenyl phosphonium ylide
B. a triphenyl boronium ion
C. a triphenyl carbocation
D. None of the above
6. Gibb's Donnan effect creates
A. Diffusion
B. Surface tension
C. Osmotic pressure
D. None of the above
7. First line defense antibody includes
A. IgA
B. IgD
C. IgE
D. IgM
8. Indication of .com in top level domain is
A. Commercial
B. Communication
C. Commodity
D. Command
9. Ibuprofen is ––––––– drug
A. Schedule C
B. Schedule H
C. Schedule X
D. Schedule J
10. Class IV drug
A. Verapamil
B. Aceclofenac
C. Cimetidine
D. Palitaxel
11. What is the pH required for activation for gastric lipase enzyme
A. 1-3
B. 4-5
C. 6-7
D. 7-8
12. Stimulation of which adrenergic receptors exerts potent anabolic effects
A. β1
B. β2
C. β3
D. α
13. World Diabetes day is celebrated on
A. 14 November
B. 15 June
C. 11 February
D. 11 January
14. Starting material for synthesis of polyvinylalcohol is
A. Vinyl alcohol
B. Poly (vinyl acetate)
C. Vinyl chloride
D. Divinyle acetate
15. Which of the following residues are not phosphorylated in the catalytic mechanism or regulation of an enzyme
A. K
B. S
C. T
D. Y
16. Mechanism of action of memantine
A. Glutamate antagonist
B. AMPA antagonist
C. NMDA antagonist
D. GABA agonist
17. Which of the following must be true for an optically active compound
A. The molecular configuration is achiral
B. The molecular configuration is chiral
C. The compound is a racemic mixture of enantiomers
D. The molecular configuration must have two or more stereogenic centers
18. Liebermann-Burchard reaction uses the reagent as ––––––––– for detection of sterol in chloroform solution
A. acetic anhydride and conc. sulphuric acid
B. succinic anhydride and conc. sulphuric acid
C. acetic anhydride and conc. nitric acid
D. acetic anhydride and picric acid
19. Which of the following does not contains heterocyclic ring
A. Fexofenadine
B. Lofexidine
C. Afimoxifene
D. Apixaban
20. An anionic surfactant is
A. Polyalkylester
B. Sodium lauryl sulfate
C. Cetyl ammonium Sulphate
D. Lecithin
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