NIPER PYQ 2019
QUIZ NO 1
TOTAL QUESTIONS = 20
1. Which one of the following is a selective 5-HT10 receptor agonist
A. Buspirone
B. Ondansetron
C. Sumatriptan
D. Cisapride
2. Deamination of 5-methyl cytosine produces
A. Uracil
B. Cytosine
C. Adenine
D. Thymine
3. Which enzyme is used for coupling of DNA helices
A. Gyrase
B. Ligases
C. Lyases
D. Isomerases
4. Which of the following are a non-reducing sugars
A. Lactose and galactose
B. Fructose and ribose
C. Isomaltose and Maltose
D. Sucrose and Trehalose
5. Which nucleic acid base is absent in RNA
A. Guanine
B. Adenine
C. Thymine
D. Uracil
6. The number of carbons in stearic acid is
A. 15
B. 16
C. 17
D. 18
7. Who discovered Oxygen
A. Joseph Priestley
B. Fritz Haber
C. Joseph Black
D. Daniel Rutherford
8. Identify the reaction in which acyl azide is converted to isocyanate
A. Lossen rearrangement
B. Schmidt reaction
C. Curtius rearrangement
D. Wolff rearrangement
9. According to Higuchi model, drug release from porous matrix is directly related to
A. time
B. square root of time
C. square of time
D. porosity
10. Position of N in purine ring are
A. 1,5,7
B. 1,3,7
C. 3,5,7
D. 1,3,5
11. Which of the following models cannot be used to evaluate model-dependent drug release
A. Higuchi's square root model Hixcon-Crowell's cube root law
B. The Weibull model
C. The first-order kinetics model
D. Gaussian distribution
12. Humira is a brand name of which of the monoclonal antibody
A. Adalimumab
B. Trastuzumab
C. Rituximab
D. Aldeslukin
13. Instantaneous distribution to most body tissues and fluids is assumed in which of the following models
A. One-compartment model
B. Two-compartment model
C. Multicompartment model
D. Data is insufficient
14. First-line anti-Parkinson drug, also used to treat hyperprolactinemia at lower doses
A. Amantadine
B. Levodopa
C. Bromocriptine
D. Benztropine
15. Agonism at which dopamine receptor subtype can result in dopamine dysregulation syndrome
A. D1
B. D2
C. D3
D. D4
16. Selegiline used in treatment of Parkinson's disease. Pick up the wrong statement about selegiline
A. It is tertiary amine with a propyne, phenylpropyl and methyl group
B. It is irreversible inhibitor of MAO B
C. It undergoes higher first pass metabolism
D. It produces the characteristic cheese effect
17. If 3 g of a drug are added and distributed throughout the compartment and the resulting concentration is 0.15 g/L, calculate the volume of the compartment
A. 10 L
B. 20 L
C. 30 L
D. 200 L
18. Glomerular filtration rate may be measured using
A. Insulin
B. para-aminohippuric acid
C. Glucagon
D. Inulin
19. Number of isoprene units in carotenoids are
A. 5
B. 6
C. 7
D. 8
20. First Satellite launched in space by India was
A. Aryabhatta
B. Chandrayaan
C. Sputnik
D. Skylab
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