NIPER-JEE PYQ 2018
QUIZ NO 7
TOTAL QUESTIONS = 20
1. Antiemetic effect of metoclopramide is mainly due to its action as
A. 5HT3 antagonist
B. D-2 antagonist
C. M-3 antagonist
D. 5HT3 agonist
2. The drug used for treatment of peptic ulcer
A. Clozapine
B. Cetirizine
C. Olanzepine
D. Pirenzepine
3. The antidote to atropine is
A. Pilocarpine
B. Pralidoxime
C. Benzotropine
D. Adrenaline
4. The maximum number of drugs approved by USFDA in last five years are ––––––––––––– in nature
A. Small organic molecules
B. Protein monoclonal antibodies
C. Protein growth hormones
D. Carbohydrates
5. A 30-membered ring macrolide antibiotic that contains O, N and containing 4 trans double bonds, three of which are conjugated is
A. Rapamycin
B. Hamycin
C. Azithromycin
D. Telethromycin
6. Hirudin is obtained from the transgenic plant
A. Brassica napus
B. Hibiscus rosasinesis
C. Raphanus sativus
D. Vinca rosea
7. Which of the following statements applies to the E2 mechanism
A. It occurs with inversion of stereochemistry
B. It occurs with racemization of stereochemistry
C. It proceeds through the more stable carbocation intermediate
D. The C-H and C-X bonds that break must be anti
8. Isoniazid is
A. Isonicotinic acid hydrazide
B. Nicotinic acid hydrazide
C. Isonicotinic acid azide
D. Isonicotinic acid semicarbazide
9. Following intravenous administration, drugs are distributed fastest to the
A. Skin, kidney, and brain
B. Liver, adipose, and brain
C. Liver, kidney, and brain
D. Liver, kidney, and adipose
10. Drug used in pulmonary hypertension
A. Bosentan
B. Amlodipine
C. Enalpril
D. Furosemide
11. Protein binding of drugs helps to maintain __ for absorption of drugs
A. Nonsink condition
B. Sink condition
C. Biological condition
D. None of the above
12. Eukaryotic ribosomal subunits are
A. 30S and 50S
B. 30S and 50S
C. 40S and 60S
D. 30S and 60S
13. Identify the incorrect statement about cannabidiol
A. It is soluble in water but insoluble in organic solvents
B. It is oxidized to a quinone
C. It cyclizes to THC under acidic conditions
D. It is approved for the treatment of epilepsy
14. In a double-stranded DNA, which of the following ratios is/are always equal to 1? A, T, G, and C denote the number of bases
A. (A + T) / (G + C)
B. (A + G) / (T + C)
C. A / G
D. (G + T) / (A + C)
15. Cyclophosphamide is converted into which active form
A. Diazonium ion
B. Aziridine ring
C. Methyl cation
D. Nitrosourea
16. Which heterocyclic ring system is present in hydralazine
A. Quinazoline
B. Quinazoline
C. Phthalazine
D. Pteridine
17. When 3-iodo-3-ethylpentane is treated with sodium methoxide in methanol, the major organic product is an ___ that is generated through an ___ mechanism
A. Ether, SN1
B. Ether, SN2
C. Alkene, E1
D. Alkene, E2
18. Zanamivir resembles
A. Salicylic acid
B. Neuraminic acid
C. Muramic acid
D. Mycolic acid
19. Kalmegh is
A. Hepatoprotective
B. Cardioprotective
C. Immunoprotective
D. Neuroprotective
20. Which of the following is 5HT1 receptor agonist used as antimigraine agents
A. Serod
B. Triptan
C. Anserin
D. Setron
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