---

1. Which of the following identified the causative agents of such deadly diseases as anthrax as tuberculosis

A. John Snow B. Robert Koch C. Ignaz Semmelweis D. Joseph Lister

---

2. A typical hard capsule gelatin type A specification with respect to pH is

A. 3.5-4.5 B. 4.5-5.5 C. 5.5-6.5 D. 6.5-7.5

---

3. Ramelton acts as

A. GABA_A potentiatornett B. Opiate receptor agonist C. Melatonin receptor agonist D. Benzodiazepine receptor agonist

---

4. Rilmenidine, an antihypertensive drug, acts as

A. Agonist of imidazoline receptors B. Antagonist of β1 receptors C. Antagonist of α1 receptors D. Antagonist of imidazoline receptors

---

5. Which of the following dienes is the most reactive in a Diels-Alder reaction

A. B. C. D.

---

6. Which of the following functional groups is likely to be present in a molecule that has peaks the IR at strong, broad peak at 1630-1820 cm^-1 but does not have peaks at 3200-3650 or 1000 1250 cm^-1

A. alcohol B. aldehyde or ketone C. ether D. ester

---

7. Which of the following is the ligand that opens the ligand-gated Ca⁺⁺ channel in the endoplasmic reticulum

A. DAG B. IP3 C. cAMP D. beta-gamma complex

---

8. The precursor for penicillin-G biosynthesis during fermentation process is

A. Phenylacetic acid B. Acetic acid C. Phenoxy acetic acid D. None of the above

---

9. 2',3'-dideoxy-5-fluoro-3'-thiacytidine, a nucleoside reverse transcriptase inhibitor is

A. Emtricitabine B. Efavirenz C. Tenofovir D. Nevirapine

---

10. The most widely used program for multiple sequence alignment is

A. FASTA B. BLAST C. RASMOL D. CLUSTAL

---

11. Which is the first plant modified by biotechnology

A. Tobacco B. Cotton C. Brinjal D. Rice

---

12. In PMR spectrum, two signals occur at 2.1 and 2.3 ppm by a spectrometer operating at 200 MHz. What is the frequency difference between their resonances in Hz

A. 0.2 Hz B. 40 Hz C. 200 Hz D. 400Hz

---

13. The Bt rice (Golden rice) is rich in which vitamin

A. beta-carotene B. beta-cetosterol C. Pantothenic acid D. Vitamin E

---

14. α-Amino ketones can be prepared by treatment of ketoximetosylates and base via

A. Beckmann rearrangement B. Schmidt Reaction C. Lossen rearrangement D. Neber rearrangement

---

15. B.C. Roy award is related to which field

A. Sports B. Engineering C. Medical D. Economics

---

16. PCR requires all of the following EXCEPT

A. Primers B. DNA ligase C. DNA polymerase D. DNA of interest

---

17. The metal present at the active site of the protein carboxypeptidase A such as renin is

A. Zinc B. Copper C. Magnesium D. Cobalt

---

18. The SGLT-2 inhibitors are

A. -glitazar B. -glinides C. -gliflozins D. -glitazones

---

19. In a magnetic field, nuclear dipoles (nuclear spins with a spin quantum number of 1/2)

A. precess around the magnetic field direction randomly B. are motionless along the direction of the magnetic field C. do not exist D. precess around the magnetic field direction at the Larmor frequency

---

20. Which of the following quantities is not changed at a different magnetic field strength

A. Chemical shift (in hertz) B. Nuclear spin population in an energy state C. J coupling constant D. Energy difference between two energy states of nuclei with non-zero spin quantum number