NIPER-JEE-QUESTION-PAPER-2015
QUIZ NO 5
TOTAL QUESTIONS = 20
1. ACE inhibitors:
A. Increase secretion of aldosterone
B. Decrease secretion of aldosterone
C. Increase secretion of vasopressin
D. Decrease secretion of ANP
2. Starting material for the synthesis of propranolol:
A. α-Naphthol
B. β-Naphthol
C. Naphthalene
D. α-Naphthylamine
3. USP Type V dissolution apparatus is used for testing of:
A. Sustained-release tablets
B. Suppositories
C. Topical and transdermal products
D. Capsules filled with pellets
4. Drug prices in India are decided by which regulatory agency?
A. NPPA
B. CDSCO
C. DCGI
D. OPPI
5. Which word is the opposite of "hypothesize"?
A. Posit
B. Speculate
C. Conjecture
D. Refute
6. 0.1 M NaCl is ___ ppm:
A. 58000
B. 5800
C. 580
D. 58
7. Karl Fischer reagent is standardized with:
A. Sodium iodide
B. Copper sulfate pentahydrate
C. Sodium tartrate dihydrate
D. Sodium thiosulfate
8. Which is the common intermediate for glucose metabolism and TCA cycle?
A. Isocitrate
B. Citrate
C. Acetyl CoA
D. β-Hydroxybutyrate
9. Drug approved by USFDA in 2015 for stroke is:
A. Ivabradine
B. Sacubitril
C. Edoxaban
D. Selexipag
10. @@@Only one of the following compounds is aromatic. Which one?
A.
B.
C.
D.
11. DEPT experiment in NMR is used to distinguish between:
A. Primary, secondary, and tertiary carbon atoms in a molecule
B. Near and distant coupling in ¹³C atoms in a molecule
C. NMR-active and NMR-inactive carbon atoms in a molecule
D. All of the above
12. Eucalyptus oil is isolated from leaves by process of:
A. Solvent extraction
B. Azeotropic distillation
C. Steam distillation
D. Leaching
13. Which organism is known as the natural genetic engineer of plants?
A. Agrobacterium radiobacter
B. Escherichia coli
C. Agrobacterium tumefaciens
D. Streptomyces sp.
14. Which of the following is a derived property?
A. Solubility
B. pKa
C. Particle size
D. Bulk density
15. A drug has pKa = 7.5. Comment on its absorption pattern:
A. Poorly absorbed from stomach
B. Poorly absorbed from intestine
C. Poorly absorbed throughout GIT
D. Absorbed only in rectum
16. Drug of choice for treatment of mild hypoglycemia in obese patients is:
A. Insulin
B. Metformin
C. Repaglinide
D. Glibenclamide
17. Tamoxifen is used in the treatment of breast cancer. It acts as:
A. Agonist of ER
B. Antagonist of ER
C. Aromatase inhibitor
D. 5α-reductase inhibitor
18. Which of the following is an antagonist of both α and β receptors?
A. Propranolol
B. Prazosin
C. Labetalol
D. Metoprolol
19. Following are the symptoms of which poisoning: pinpoint pupils, photophobia, blurred vision?
A. Mushroom
B. Morphine
C. Belladonna
D. Organophosphorus
20. Drug of choice for treating organophosphorus poisoning is:
A. Pralidoxime + Atropine
B. Acetylcholine
C. Neostigmine + Pralidoxime
D. Acetyl CoA
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