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1. Which is associated with vaginal carcinoma in female offspring?

A. Diethylstilbestrol B. Phenytoin C. ACE inhibitors D. Indomethacin

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2. Which one of the following antimalignancy drugs is most nephrotoxic?

A. Vincristine B. Cisplatin C. Cyclophosphamide D. Methotrexate

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3. Which one of the following microscopic techniques can be used to study the contour of proteins?

A. Confocal microscopy B. TEM C. AFM D. SEM

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4. The action of insulin is potentiated by:

A. Sulphonylureas B. Glucagon C. Biguanides D. None of the above

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5. Cyproheptadine has all of the following actions EXCEPT:

A. Antimuscarinic actions B. Antihistaminic actions C. Antiserotonergic actions D. Antiadrenergic actions

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6. Which one is the correct order of drug release?

A. Disintegration, Disaggregation, Dissolution, Dissociation B. Disaggregation, Disintegration, Dissolution, Dissociation C. Disintegration, Disaggregation, Dissociation, Dissolution D. Disaggregation, Disintegration, Dissociation, Dissolution

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7. Chirality of DNA is due to:

A. The bases B. Base stacking C. Hydrogen bonds between bases D. Deoxyribose

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8. Design of experiments implies:

A. Good instruments used in the lab B. Team meetings in product trials C. A method to find factor effects D. Aesthetic quality of products

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9. The half-life of the first-order reaction is independent of:

A. Square of final substrate B. Initial substrate concentration C. Final substrate concentration D. Cube root of final substrate concentration

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10. Which of the following effects can be explained by Franck-Condon Principle?

A. Overtone in IR spectrum B. Combination mode in vibrational spectrum C. Largest intensity of fundamental D. Largest intensity of overtone

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11. When 1-pentanol is heated with HCl/ZnCl2, 1-chloropentane is the major organic product. The reaction proceeds through an ____ mechanism, and ____ is produced as a by-product:

A. SN1, H2 B. SN2, H2O C. SN1, H2O D. SN2, H2

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12. Which of the following m/z values is the base peak for benzyl alcohol (PhCH2OH)?

A. 77 B. 108 C. 91 D. 17

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13. Prodrugs cannot have different modes of:

A. Absorption B. Excretion C. Metabolism D. Mode of action

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14. An amendment was introduced in the Drugs & Cosmetics Act 1940 to prohibit advertisement of drugs specified in Schedule H, Schedule H1, or Schedule X. When was this amendment introduced?

A. April 2015 B. March 2013 C. May 2012 D. April 2008

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15. Bilobalide, a chemical constituent of Ginkgo biloba, is:

A. Monoterpenoid B. Sesquiterpenoid C. Diterpenoid D. Triterpenoid

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16. Domperidone is:

A. Antimotility B. Promotility C. D₂ agonist D. Muscarinic antagonist

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17. Convolvulus pluricaulis L. (Fam. Convolvulaceae) is commonly known as:

A. Shatavari B. Gurmar C. Ashwagandha D. Shankhpushpi

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18. What is the maximum shelf life in months permissible under the Drugs and Cosmetics Act?

A. 24 months B. 36 months C. 48 months D. 60 months

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19. Which of the following words does not appear in the official definition of 'drug' in India?

A. Prevention B. Cure C. Diagnosis D. Mitigation

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20. An inanimate object that transmits infectious agents between hosts is most appropriately called:

A. Fomite B. Carrier C. Vector D. Reservoir