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1. An organic compound is composed of C, H, and N. It shows a molecular ion at m/z = 112 amu in the mass spectrum. What is the plausible molecular formula for this compound?

A. C₇H₁₄N₂ B. C₆H₁₂N₂ C. C₆H₁₀N₂ D. C₇H₁₂N2

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2. In hybridoma technology, myeloma cells lacking HGPRT area used in HAT medium. In this medium what is the role of aminopterine?

A. To block the cell cycle in myeloma cells B. To block the pathway for nucleotide synthesis C. To facilitate fusion of myeloma B cells and antibody-producing cells D. To facilitate production of antibody-producing cells

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3. Which one of the following antifungal drugs produces its effect by inhibiting sterol synthesis in fungal cells?

A. Ketoconazole B. Caspofungin C. Amphotericin D. Griseofulvin

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4. The movement of extracellular fluid into the cell by the process of vesicular transport is called:

A. Exocytosis B. Receptor-mediated endocytosis C. Pinocytosis D. Transcytosis

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5. Opalux is:

A. Enteric coating material B. Binder C. Color coating material D. Polishing material

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6. For which of the following methods is it most important to use an internal standard?

A. GC with manual injection B. GC with autosampler injection C. HPLC with manual injection D. HPLC with autosampler injection

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7. Which G protein activates adenylate cyclase?

A. Gs B. Gi C. Gi D. Gq

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8. The type of chromatography wherein the analyte ions in the mobile phase are attracted to the counter ions in the stationary phase is:

A. Ion-pair chromatography B. Size exclusion chromatography C. Ion-exchange chromatography D. Affinity chromatography

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9. Which one is the biggest company producing API?

A. Dr. Reddy’s B. Sun Pharma C. Aurobindo D. TAPI (Teva API)

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10. COOH The given compound is which isomer?

A. ERYTRO B. THREO C. SYN D. NONE

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11. Proteins associated with Alzheimer’s disease is:

A. Synuclein B. Tau C. β-glucosidase D. α-Galactosidase

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12. Circle the statement that reflects the action of amylin.

A. Opposes the action of insulin B. Enhances gastric emptying C. Promotes glucagon release D. Delays gastric emptying

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13. Cerebral malaria is caused by:

A. Plasmodium vivax B. Plasmodium ovale C. Plasmodium falciparum D. Plasmodium malariae

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14. All of the following are RNA viruses EXCEPT:

A. Dengue B. Swine flu C. Ebola D. Hepatitis B

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15. The peptide bond is rigid because it is a:

A. Single bond B. Partial double bond C. Double bond D. Triple bond

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16. In competitive inhibition:

A. Km increases, Vmax constant B. Km decreases, Vmax constant C. Km constant, Vmax increases D. Km decreases, Vmax increases

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17. Which natural polymer is used in the production of explosives?

A. Carrageenan B. Alginate C. Agar D. Xanthine

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18. Nutraceuticals available in the market from marine sources are largely from:

A. Bacteria B. Fungi C. Diatoms D. Macro algae

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19. In human genome, approximately ___ of the DNA codes for proteins:

A. 10% B. 2% C. 50% D. 20%

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20. In Parkinson's disease, there is a predominant loss of dopaminergic neurons primarily in:

A. Substantia nigra B. Cerebellar cortex C. Cerebral cortex D. Locus coeruleus