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1. Which of the following is the main active component of betel nut?

A. Ephedrine B. Chlorogenic acid C. Hypericin D. Arecoline

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2. A demonstration that a particular instrument or device produces results within specified limits by comparisons with those produced by a reference or traceable standard over an appropriate range of measurements is:

A. Validation B. Calibration C. Performance qualification D. Examination

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3. What is the fall height of the tablets in the friabilator during friability testing?

A. 6 inches B. 6 cm C. 10 cm D. 3 inches

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4. Cypriol oil is obtained from:

A. Nagarmotha B. Bach C. Kalijiri D. Kantaakari

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5. Khellin is present in:

A. Bishop’s weed B. Bind weed C. Blue grass D. Blue berry

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6. Which of the following has the least cardiotoxicity?

A. Isoflurane B. Enflurane C. Bupivacaine D. Ropivacaine

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7. Protection–deprotection and coupling between two amino acids components are important steps in peptide synthesis. One of the following is NOT used as a protecting group in the peptide synthesis.

A. Benzyloxycarbonyl B. N, N'-dicyclohexylcarbodiimide (DCC) C. 9-Fluorenylmethoxycarbonyl (FMOC) D. tert-Butoxycarbonyl (BOC)

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8. Gutta-percha is made of:

A. cis-poly 1,4-polyisoprene B. trans-poly 1,4-polyisoprene C. paraphenylene diamine and terephthaloyl chloride D. Di-isocyanate and diol

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9. All of the following statements about meglitinide are true, except:

A. Act by stimulating insulin release B. Decrease Postprandial Hyperglycemia C. Hypoglycemia is less common than with sulfonylureas D. Act by decreasing insulin resistance

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10. In the proton NMR, in what region of the spectrum does one typically observe hydrogens bound to the aromatic ring?

A. 2.0-3.0 ppm B. 4.5-5.5 ppm C. 7.0-8.0 ppm D. 9.0-10.0 ppm

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11. The major difference between typical and atypical antipsychotics is that:

A. Atypical antipsychotics cause minimal or no increase in prolactin B. Typical antipsychotics cause tardive dyskinesia C. Typical antipsychotics are available as parenteral preparations D. Atypical antipsychotics cause substantial sedation

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12. Which of the following is used to decrease the toxicity of amphotericin B?

A. Dose reduction B. Liposomal delivery systems C. Supplementing glucose D. Giving it along with flucytosine

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13. Which of the following is nonpatentable as per Indian Patents ACT, 1970?

A. A new method of cardiac bypass surgery B. A genetically modified microorganism C. A novel machine for recording of ECG D. A novel method of extraction from a known plant drug

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14. A bioinformatics tool used to find the sequence similarity in the subunit of hemoglobin is:

A. FASTA B. HUMMER C. PSI-PLOT D. BLAST

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15. Alkalinization of urine is done during administration of which of the following chemotherapeutic drugs?

A. Methotrexate B. Ara-C C. Cisplatin D. Ifosfamide

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16. A nucleic acid was analyzed and found to contain 32% adenine, 18% guanine, 17% cytosine, and 33% thymine. The nucleic acid must be:

A. Single-stranded RNA B. Single-stranded DNA C. Double-stranded RNA D. Double-stranded DNA

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17. Which of the following substances acts to increase the release of Ca²⁺ from endoplasmic reticulum?

A. Inositol triphosphate B. Parathyroid hormone C. 1,25-dihydroxycholecalciferol D. Diacylglycerol

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18. @@@Match the plants with their families. 1. Theobroma cocoa - P. Palmae 2. Areca catechu - Q. Apocynaceae 3. Hallorrheantidyssentrica - R. Liliaceae 4. Veratrum album - S. Sterculiaceae

A. 1-S, 2-R, 3-Q, 4-P B. 1-R, 2-S, 3-P, 4-Q C. 1-S, 2-P, 3-Q, 4-R D. 1-Q, 2-P, 3-S, 4-R

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19. Fluoride, used in the collection of blood samples for glucose estimation to prevent glycolysis in the blood sample, inhibits the enzyme:

A. Glucokinase B. Hexokinase C. Enolase D. Glucose-6-phosphatase

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20. International Bureau of World Intellectual Property Organisation is:

A. New York B. Geneva C. Zurich D. Toronto