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1. The following drugs have significant drug interaction with digoxin, except:

A. Cholestyramine B. Thiazide diuretics C. Quinidine D. Amlodipine

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2. By which method are pyrogens NOT removed?

A. Adsorbing on adsorbent B. Ultrafiltration C. Autoclaving D. Distillation

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3. At what temperature does the α-form of cocoa butter melt?

A. 34.5 B. 27-28 C. 22 D. 18

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4. Exclusivity granted to the first generic applicant after FDA approval:

A. 60 days B. 90 days C. 10 days D. 180 days

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5. Which one of the following is NOT a rational drug combination?

A. Methotrexate + Probenecid B. Imipenem + Cilastatin C. Sulfadoxine + Pyrimethamine D. Ampicillin + Clavulanic acid

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6. The TATA box is a(n):

A. Sequence common to the promoter region of many genes B. Square-shaped sequence C. Enhancer consensus sequence D. Activator sequence necessary for proper translation

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7. All are RNA polymerase inhibitors, EXCEPT:

A. Rifampicin B. Fusidic acid C. Caspofungin D. Doxorubicin

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8. Antioxidant which is water-soluble?

A. Propyl gallate B. Sodium formaldehyde sulphoxylate C. Butylated hydroxytoluene D. Butylated hydroxyanisole

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9. Under the D&C Act, ‘prescription drugs’ fall under:

A. Schedule H B. Schedule X C. Schedule G D. All

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10. What is the pH of the solution formed when 0.060 moles NaOH is added to 1.00 L of 0.050 M HCl?

A. 12.78 B. 2.00 C. 7.00 D. 12.00

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11. Arrange the following groups in decreasing order of priority for E/Z nomenclature, with the highest priority group listed first:
P) -CH(CH₃)₂

Q) -F
R) -CH₂CH₂CH₂CH₃

A. Q > P > R B. Q > R > P C. P > R > Q D. R > P > Q

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12. The concentration of plasticizers as glycerol or sorbitol for soft gelatin capsule?

A. Between 1:10 and 4:10 B. Between 4:10 and 8:10 C. Between 8:10 and 10:10 D. Between 1:10 and 10:10

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13. Which of the following is not an autoimmune disease?

A. Multiple sclerosis B. Type II diabetes C. Systemic lupus erythematosus D. Grave's disease

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14. ‘Capill’ is a capsule shell made up of –––––––––.

A. Pork gelatin B. Goat gelatin C. Starch hydrolysate D. HPMC

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15. Newtonian fluid viscosity is measured by –––––––––.
P. Ostwald-Cannon-Fenske viscometer
Q. Hoeppler Falling ball viscometer
R. Cup and Bob viscometer
S. Cone and Plate viscometer

A. P and Q B. Q and R C. P and S D. R and S

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16. Fiscal Policy is connected with:

A. Issue of currency B. Exports and imports C. Public revenue and expenditure D. None of these

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17. Apoptosis is triggered by –––––––.

A. Nitric oxide B. Superoxide dismutase C. BCL 2 D. p53

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18. Apoptosis can involve a series of proteases called ___ which cleave substrates:

A. CDKs B. PARPs C. Caspases D. Microtubules

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19. Megaloblastic anaemia occurs due to deficiency of which vitamin?

A. B6 B. B2 C. B5 D. B12

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20. Choose the wrong option regarding morphine:

A. Causes vasodilation, uterine relaxation B. Lowers BP C. Constricts pupils D. Causes respiratory acidosis