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1. In supercritical fluid chromatography, if using packed columns, the most common stationary phase is:

A. A methyl-type stationary phase bonded to silica (like DB-1) for GC B. An aromatic-type stationary phase bonded to silica C. An octadecyl stationary phase bonded to silica D. Uncoated silica

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2. Which of the following compounds would have the highest boiling point?

A. CH₃CH₂CH₂CH₃ B. CH₃NH₂ C. CH₃OH D. CH2F₂

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3. Which one will undergo faster decarboxylation reaction?

A. Formic acid B. Malonic acid C. Maleic acid D. Fumaric acid

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4. RAFTS in cells function to:

A. Compartmentalize cellular processes B. Carry the extracellular ingredients into the cell C. Pinocytosis D. All of the above

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5. Ludipress composition?

A. 93% Lactose monohydrate, 3.5% Kollidon 30, and 3.5% Kollidon CL B. Sodium Starch Glycolate C. Sucrose, Invert sugar, Cornstarch, and Magnesium stearate D. 90% D-mannitol, 5% Kollidon CL-SF, and about 5% polyvinyl acetate

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6. @@The CMR spectrum of an unknown compound shows 6 absorptions, and the PMR spectrum shows 5 absorptions. Which of the following compounds is the unknown compound?

A. B. C. D.

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7. Which are the THREE R's followed by the animal ethics committee?
P) Replacement
Q) Reduction
R) Refinement
S) Rehabilitation

A. P, Q, and R B. P, R, and S C. Q, R, and S D. P, R, and S

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8. Which are the recently banned drugs due to cardiotoxicity?
P) Rosiglitazone
Q) Propoxyphene
R) Tolcapone
S) Alpidem

A. P and Q B. P and R C. Q and R D. R and S

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9. Which of the following changes to morphine will cause it to become a m-receptor antagonist?

A. NCH₂CH=CH₂ for NCH₃ B. NC₅H₅ for NCH₃ C. 6-OH to 6-H D. 3-OCH₃ for OH

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10. If C is the concentration of dissolved drug and Cs is the saturation concentration, in which case are the sink conditions said to be maintained?

A. C < 20% of Cs B. C > 20% of Cs C. C < 10% of Cs D. C > 10% of Cs

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11. Which one of the following drugs does not have a 7-membered ring?

A. Doxepine B. Paroxetine C. Olopatadine D. Ketotifen

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12. CO₂ is a greenhouse gas because it absorbs heat radiation from the earth. Which is a true statement?

A. CO₂ absorbs visible light, but not IR radiation B. CO₂ absorbs IR radiation, but not visible light C. CO₂ never absorbs any radiation D. CO₂ absorbs both visible light and IR radiation

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13. Fluorescence is observed for all of the following compounds, EXCEPT:

A. Quinoline B. Isoquinoline C. Pyridine D. Indole

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14. The risk of kernicterus increases with the use of:

A. Ceftriaxone B. Phenobarbitone C. Ampicillin D. Sulphonamide

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15. Which of the following drugs do not reduce gastric motility?

A. Glycopyrrolate B. Atropine C. Domperidone D. Loperamide

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16. A 30-carbon precursor of the steroid nucleus, lanosterol, is:

A. Farnesyl pyrophosphate B. Geranyl pyrophosphate C. Isopentenyl pyrophosphate D. Squalene

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17. The absorption of aspirin is best at Ph –––––––––.

A. 1-2 B. 3-5 C. 5-7 D. 7-8

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18. Carrier-mediated transport follows kinetics of –––––––––.

A. Zero order B. First order C. Pseudo first order D. Michaelis-Menten

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19. Which of the following is not enclosed by a bilayer of phospholipid?

A. Nucleus B. ER C. Microsome D. Golgi Apparatus

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20. Gastrointestinal motility is increased by which drug?

A. Domperidone B. Morphine C. Cisapride D. Loperamide