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1. Which of the following is not a direct tax?

A. Wealth Tax B. Income Tax C. Estate Duty D. Sales Tax

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2. Vitamin E has ___ possible stereoisomers:

A. 3 chiral centers, therefore 8 B. 2 chiral centers, therefore 4 C. 4 chiral centers, therefore 16 D. 1 chiral center, therefore 2

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3. @@@Which of the following is an intermediate in the reaction of benzene with CH₃Cl and AlCl₃?

A. B. C. D.

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4. The most stable conformational isomer of cis-1-bromo-2-chlorocyclohexane will have:

A. Both halide atoms in axial positions B. Both halide atoms in equatorial positions C. The bromine atom in an axial position and the chlorine atom in an equatorial position D. The bromine atom in an equatorial position and the chlorine atom in an axial position

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5. Gastroretentive systems are:

A. Hydrodynamically balanced systems B. High density systems C. Bioadhesive systems D. All

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6. Lactate formed in muscles can be utilized through:

A. Rapoport-Luebering cycle B. Glucose-alanine cycle C. Cori's cycle D. Citric acid cycle

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7. Coenzyme A contains a vitamin which is:

A. Thiamin B. Ascorbic acid C. Pantothenic acid D. Niacinamide

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8. Which one of the following is not a calcium channel blocker:

A. Nifedipine B. Aniskiren C. Bepridil D. Diltiazem

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9. Insulin can't be absorbed orally, as it is:

A. A macromolecule B. Poorly permeable C. Susceptible to gastric proteolytic enzymes D. Insoluble in lipid

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10. Which of the following drugs is most likely to cause loss of equilibrium and auditory damage?

A. Amikacin B. Ethambutol C. Isonazid D. Rifabutin

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11. Indirectly acting sympathomimatic shock is:

A. Dopamine B. Tyramine C. Phenylephrine D. Isoprenaline

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12. The therapeutic index of a drug is a measure of its –––––––.

A. Safety B. Efficacy C. Potency D. Dose variability

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13. The Indian Supreme Court denied a patent for the Novartis breakthrough medicine Glivec. Its active constituent is –––––––.

A. Imatinib B. Sorfenib C. Infliximab D. Abciximab

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14. Fundamental rights of an Indian Citizen are ___ in number:

A. 3 B. 4 C. 5 D. 6

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15. Lipitor is the brand name of which drug?

A. Atorvastatin B. Colestipol C. Gemfibrozil D. Lisinopril

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16. Least-developed countries have time until for pharmaceutical patents, to ensure that their laws and practices conform with the TRIPS:

A. 2016 B. 2012 C. 2020 D. 2025

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17. The science of tribology is the study of:

A. Biocompatibility between two membranes B. Friction C. Organisms that colonize biocompatible surfaces D. How bacteria group together on a contact lens surface

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18. The Bolar provision in the Indian Patent Act allows affordable generic equivalents of drugs to be brought into the market:

A. Before expiry of patent B. After expiry of patent C. Is not concerned at all with the patent D.

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19. Nonlinear pharmacokinetics means:

A. Drug serum concentrations decrease in a straight line when plotted on a Concentration-Time graph B. Drug serum concentrations decrease in a straight line when plotted on a log Concentration-Time graph C. Steady-state drug serum concentrations change proportionally to dose D. Steady-state drug serum concentrations change non-proportionally to dose

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20. Which one of these is a non-patentable invention?

A. A method of testing B. A method of agriculture and horticulture C. Any substance which is not applied for treatment or to prevent a disease D. Microorganisms