NIPER-JEE-QUESTION-PAPER-2013 QUIZ NO 3 TOTAL QUESTIONS = 20 Mock Test Quiz Free MCQ pyqonline.com

NIPER-JEE-QUESTION-PAPER-2013
QUIZ NO 3
TOTAL QUESTIONS = 20

1. Antiparkinsonian drugs act by ______.

A. Increasing dopamine activity in CNS B. Reducing acetylcholine activity in CNS C. Increasing blood flow towards brain D. All

2. Methotrexate ______.

A. Competitively inhibits dihydrofolate synthetase (DHFS) B. Competitively inhibits dihydrofolate reductase (DHFR) C. Competitively inhibits thymidylate reductase (THR) D. Competitively inhibits thymidylate synthetase (THS)

3. Which of the following information can be derived from molecular docking?

A. Predicts the preferred orientation of drug in drug-target complex B. Predict the strength of association or binding affinity between two molecules C. Prediction of type of signal produced by drug-target interaction D. All of the above

4. COMSIA is associated with ______.

A. Virtual screening B. Molecular docking C. QSAR D. ADME prediction

5. Enantiomers exhibit ______.

A. Absolute isomerism B. Relative isomerism C. Optical isomerism D. All

6. α- and β-form of cyclic glucose are known as ______.

A. Epimers B. Anomers C. Enantiomers D. Diastereoisomers

7. In CYP450, what is indicated by 450?

A. λ of absorption of light by P450 enzyme B. Location of enzyme C. Number of iso-enzyme of P450 D. None of the above

8. Which of the following HPLC Grade solvent is used for peptide and protein analysis?

A. Dimethylsulfoxide (DMSO) B. Dimethylformamide (DMF) C. Acetonitrile D. All

9. Specificity of enzyme indicates ______.

A. Stereospecificity B. Regiospecificity C. Chemospecificity D. All

10. Octadecyl carbon chain (C18) bonded silica column is used in ______ chromatography.

A. Normal phase B. Reverse phase C. Ion pair D. Size exclusion

11. Reverse phase chromatography

A. Non-polar stationary phase B. Polar stationary phase C. Dipolar stationary phase D. None

12. What is the normal fasting blood sugar in humans?

A. 100 mg/dl (5.6 mmol/L) B. 120 mg/dl (6.6 mmol/L) C. 83 mg/dl (4.6 mmol/L) D. None

13. Which of the following is used as a reducing agent?

A. PCl₅ B. HNO₃ and H₂SO₄ C. LiAlH₄ in ether D. KMnO₄

14. Right to Information Act came into force in ______.

A. 2000 B. 2002 C. 2005 D. 2007

15. Which of the following solvent is used in reversed-phase chromatography?

A. Heptafluorobutyric acid B. Benzene C. Diethyl ether D. All

16. Which of the following is a natural antioxidant in the human body?

A. Glutathione B. Melatonin C. Tocotrienols D. ALL

17. Which of the following stains is used to examine viable microbes?

A. Fluorescent dyes B. Schiff’s reagent C. Crystal violet D. Ruthenium-III

18. ______ is the bulk property detector in HPLC.

A. UV-VIS detector B. Fluorescence detector C. R.I detector D. All

19. Bragg’s Law states nλ = 2d sinϕ, where ϕ =

A. Plan angle B. Scattering angle C. Crystalline angle D. All

20. _____ is the universal HPLC detector.

A. UV-VIS detector B. Fluorescence detector C. RI detector D. Electrochemical detector

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