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1. Nobel prize for HIV virus detection was awarded to ––––––––.

A. Harald zur Hausen B. Françoise Barré-Sinoussi C. Luc Montagnier D. B and C both

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2. The oil-to-water partition coefficient of a substance gives us an idea about its?

A. Lipophilicity B. Hydrophobicity C. Both D. None

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3. Which of the following is true about Anandamide?

A. It is N-arachidonoylethanolamine (AEA) B. Endogenous cannabinoid neurotransmitter C. Involved in functions of the immune system D. All of the above

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4. Endotheline is ––––––––.

A. Vasoconstricting peptides B. Endothelial cells of blood vessels C. Neurotransmitters D. Protein

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5. The first planning commission of India was set up on:

A. 15 March 1938 B. 15 March 1950 C. 26 January 1949 D. 15 August 1950

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6. One of the following methods is not used for the determination of pKa:

A. Sirius Potentiometric Method B. Yesuda Shedlovsky Experiment C. Shake Flask Method D. UV Spectrophotometer

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7. What does Bredt's rule state?

A. SN2 reactions always produce inversion of configuration B. 3° carbocation is more stable than 2° C. Symmetric compounds do not have dipole movements D. Double bond cannot be placed at the bridgehead of a bridged ring system

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8. Histone deacetylase inhibitors can be used as ––––––––.

A. Antidiabetic B. Antihypertensive C. Antiallergic D. Antidepressant

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9. HLB of o/w emulsifier is ––––––––.

A. 1–3 B. 3–6 C. 7–9 D. 8–18

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10. How many members are required to form a society?

A. 2 B. 5 C. 7 D. No minimum limit

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11. Aliskiren is ––––––––.

A. ACE inhibitor B. Renin inhibitor C. Renin antagonist D. Aldosterone antagonist

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12. Penicillin amidase enzyme ––––––––.
Converts penicillin into 6-APA in alkaline conditions
In acidic conditions, it is used to synthesize penicillin from 6-APA

A. I is true, II is false B. I is false, II is true C. I and II are true D. I and II are false

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13. Which of the following is false regarding clinical trials?

A. Phase 1: done on 20-50 healthy volunteers for estimation of safety and tolerability of drug. B. Phase 2: controlled clinical trials. Done on up to 1000 population of patients. C. Phase 3: expanded controlled or uncontrolled clinical trials. Done on upto 3000 to 10000 popullation of patients. D. None of the above

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14. Which of the following reactions is used to synthesize isoquinoline?

A. Bechamp B. Benkeser C. Birch D. Bisler Napieralski

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15. @@@

A. Bechamp reduction B. Benkeser reduction C. Birch reduction D. Wolff-Kishner reduction

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16. Rota rod apparatus is used in the study of ––––––––.

A. Anticonvulsant B. Anti-anxiety C. Muscle relaxant D. Antidepressants

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17. Catalepsy means ––––––––.

A. Loss of consciousness with rigidity of muscles that keeps limbs in a fixed condition B. Chronic attack of seizures due to electrical imbalance in the brain C. Loss of consciousness after tonic-clonic seizures D. None of the above

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18. GHOST peak in chromatography is due to ––––––––.

A. Solvent B. Column packing C. Temperature variation D. Impurity

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19. Alzheimer disease is caused by ––––––––.

A. Increase in dopamine level in a certain part of the brain B. B-amyloid and tau protein level increased in the brain C. Increase in acetylcholine level in the brain D. Decrease in dopamine level in a certain part of the brain

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20. The RNA strand is 1st reverse transcribed into its complementary DNA, followed by amplification of the resulting DNA using PCR. This technique is known as:

A. RNA-PCR B. RNA-RT-PCR C. RT-PCR D. RT-DNA-PCR