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1. When is a statutory meeting held in a company –––––– from the date at which the company is entitled to commence business?

A. Within a period of not less than one month nor more than six months B. Within a period of not less than six months nor more than twelve months C. Both D. Depends upon financial situation

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2. Identify non-ionic surfactant:

A. Sodium lauryl sulfate B. Spans C. Benzalkonium chloride D. Lecithin

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3. _____ is the example of non-irritating purgative:

A. CMC B. Anthraquinone C. Triphenylmethane D. Ricinolic acid

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4. Purgative action of phenolphthalein is due to ––––––––.

A. Phthalic acid B. Phenol C. Triphenylmethane D. None of the above

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5. Podophyllin is used for ––––––.

A. Ovarian cancer B. Constipation C. Irritable bowel syndrome (IBS) D. Diarrhea

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6. If a drug is highly protein-bound, then it shows ––––––.

A. More efficient diffusion into cell membranes B. High potency C. Low potency D. Low biological half-life

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7. Gossypol shows which kind of isomerism?

A. Optical isomerism B. Configurational isomerism C. Atropisomers D. R and S isomerism

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8. Ephedrine exists in how many stereoisomeric forms?

A. 1 B. 2 C. 3 D. 4

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9. Chemically betaine is –––––––.

A. Cation B. Anion C. Zwitterions D. None of the above

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10. Which of the following H2 receptor antagonists has the highest affinity for CYP450?

A. Nizatidine B. Ranitidine C. Cimetidine D. Famotidine

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11. Which of the following drugs has an effect on the conduction of the heart?

A. Nifedipine B. Verapamil C. Atenolol D. All of the above

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12. During fermentation of penicillin, the pH is first adjusted to 2. Why?

A. For maximum growth of Penicillium chrysogenum B. For maximum yield C. Penicillin exists as an undissociated acid so it is soluble in organic solvents D. To remove the impurity

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13. _____ is used as a precipitating agent during penicillin recovery in penicillin fermentation:

A. Potassium acetate B. Potassium hydroxide C. Silver nitrate D. Sodium hydroxide

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14. Delta value of ETHYLENE = 2.3–2.7 ppm, whereas that of ACETYLENE is = –––––––.

A. 2.7–3.2 ppm B. 6–9 ppm C. 4.5–6.5 ppm D. 1.1–3.0 ppm

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15. The correct description for polarity of acetone compared with methanol is ––––––.

A. Acetone > methanol B. Acetone < methanol C. Acetone = methanol D. Both are non-polar

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16. Amino acid which is described as an imino acid ––––––.

A. Proline B. Lysine C. Tyrosine D. Leucine

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17. When UV light falls on a molecule, it causes –––––––.

A. Excitation of bonds B. Excitation of nucleases C. Excitation of molecule D. Excitation of electrons

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18. Why is multidrug treatment given in TB?

A. To avoid resistance B. To minimize side effects C. To reduce the duration of therapy D. To reduce the cost of therapy

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19. Far IR region lies in the range of –––––––.

A. 0.8–2.5 µm B. 2.5–15 µm C. 15–200 µm D. 200–400 µm

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20. Allosteric binding means ––––––––.

A. Binding of the substrate at the active site of the enzyme B. Binding to a site other than the active binding site on the same enzyme C. Binding to the enzyme-substrate complex D. Binding to an endogenous substrate