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1. Instantaneous distribution to most body tissues and fluids is assumed in which of the following models

A. One-compartment model B. Two-compartment model C. Data is insufficient D. Multicompartment model

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2. A+B > C+D, B+E = 2C, C+D > B+E which of the following is correct?

A. C+D =2C B. B+E > A+B C. A+B > 2C D. A+B < C+D

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3. Which of the following class of drug causes QT prolongation?

A. Antiarrhythmic class III B. COX II inhibitor NSAID C. Isosorbide antianginal D. Artemisinin antimalarial

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4. Nucleotides are attracted to each other by which kind of bond?

A. Phosphodiester B. Hydrogen C. (b) and (c) both D. Sulphide

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5. Which of the following drug delivery systems comprises a hydrophobic core and a hydrophilic surface

A. Reverse micelles B. None of the above C. Micelles D. Liposomes

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6. Thiomers are thiolated polymers. These have which of the following action?

A. Mucoadhesion B. Efflux pump, enzyme inhibition C. All of the above D. Permeation enhancement

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7. Isoelectric point of insulin is 5. How one can make its long acting formulation?

A. Both of the above B. None of above C. Increase pH of formulation above isoelectric point D. Decrease pH formulation above isoelectric point

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8. The N–O stretching vibrations in nitroalkanes occur near cm⁻¹

A. 1350–1550 B. 3400–3600 C. 650–850 D. 1000–1200

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9. Which of the following is the toxic compound of linseed

A. Scopoletin B. Linamarin C. Ricin D. Arabinoxylane

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10. Which phytohormone induces seed dormancy

A. Ethylene B. Auxin C. Gibberellin D. Abscisic acid

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11. Which one is not soft/ambient ionization technique

A. Fast atom bombardment (FAB) B. Atmospheric-pressure chemical ionization (APCI) C. Electron ionization (EI) D. Chemical ionization (CI)

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12. Definition of 'Startup' includes all of the following EXCEPT

A. Even after expiration of five years turnover is less than 5 crores B. The turnover for any of the financial years, within five years of its incorporation or registration, did not exceed rupees twenty-five crores C. It is working towards innovation, development, deployment or commercialization of new products, processes or services driven by technology or intellectual property D. More than five years have not lapsed from the date of its incorporation or registration

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13. Patisiran is an approved drug. Chemically it is

A. a double-stranded short interfering RNA B. a single-stranded DNA C. a double-stranded short interfering RNA D. Protein

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14. Formula for angle of repose is..........

A. tan θ=r/h B. tan θ=h/r C. tan^-1 θ=r/h D. tan^-1 θ=h/r

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15. Ethyl-acetoacetate is prepared from ethyl acetate by the _________

A. Aldol condensation B. Benzoin condensation C. Claisen condensation D. Dieckmann condensation

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16. Morphine shows its action by acting on _____ receptor

A. µ and δ B. γ and µ C. µ D. κ and δ

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17. Which of the following is hydrophobic?

A. DMSO B. Ethanol C. PEG D. Stearic acid

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18. As per DPCO 2013, what is the method of drug pricing

A. Cost based pricing B. Market based pricing C. Patient affordability D. Manufacturing expenses + Maximum Allowable Post Manufacturing Expenses

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19. Polymethyl methacrylate (PMMA) is known as

A. Nylon-6 B. Teflon C. Bakelite D. Perspex

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20. A+B = 100 A-B = 24, so which is the larger number?

A. B=62 B. A=38 C. A=62 D. B=38