NIPER-JEE MIX QUESTIONS
QUIZ NO 10
TOTAL QUESTIONS = 20
1. Fomivirsen is an example of which of the following biological products
A. A monoclonal antibody
B. An siRNA molecule
C. A liposomal formulation
D. An antisense oligonucleotide
2. What is the indication of flow property
A. Bridging
B. Arching
C. Rat holing
D. Angle of repose
3. Cilostazol, a drug used in the treatment of intermittent claudication, inhibits which phosphodiesterase enzyme for its clinical effect
A. PDE4
B. PDE6
C. PDE5
D. PDE3
4. Synonym of MAGNANIMOUS _____
A. Attractive
B. Love
C. Kind
D. Generous
5. Independently folded functional unit of a protein is called a
A. module
B. motif
C. domain
D. fold
6. Which of the following are ambident nucleophiles
A. –SCN, CN, -CH
2
C(O)CH
3
B. –Cl, -Br, -F
C. –OH, -OR, -OCOR
D. BF
3
, AlCl
3
, SOCl
2
7. The time taken for 5% of a drug to decompose by first-order kinetics is
A. 0.022/k1
B. 0.105/k1
C. k1/0.051
D. 0.051/k1
8. Tween 40 is __________
A. Ployoxyethylene (20) sorbitan monooleate
B. Polyoxyethylene (20) sorbitan monolaurate
C. Polyoxyethylene (20) sorbitan monolaurate
D. Polyoxyethylene (20) sorbitan monopalmitate
9. Deflocculated suspension shows ______ flow properties
A. Pseudoplastic
B. Dilatant
C. Plastic
D. Thixotropic
10. The metabolic pathway that occurs partly in mitochondria and partly in cytosol is:
A. Urea cycle
B. Oxidative phosphorylation
C. Glycolysis
D. TCA cycle
11. In QSAR studies the biological activity is expressed in terms of concentration C. The expression used is
A. Any of the above
B. log C
C. C
D. log 1/c
12. Placket-Bumman design is _________
A. Computer aided design
B. Drug design tool
C. Type of HPLC column design
D. Type of experimental design
13. Which of the following is false about secondary structure of protein?
A. All peptide bond does not participate in hydrogen bonding
B. Extensive hydrogen bonding stabilizes the secondary structure
C. α-helix is unstable conformation because it formed spontaneously with highest energy
D. Twisting and folding of polypeptide produces secondary structure
14. Who has been appointed as the head of the committee formed by the government to address the issues of drug security in the country in the context of Novel Corona virus outbreak
A. Eswara Reddy
B. Gita Mittal
C. Vashishtha Narayan Singh
D. R.K. Mathur
15. Glycolysis occur in ________
A. Cytosol
B. Ribosome
C. Golgi apparatus
D. Mitochondria
16. One part per million is the same as
A. 1ng/mg
B. All of the above are correct
C. 1 mg/kg
D. 1μg/g
17. Peripheral & central emesis is caused by _____
A. Ergot
B. Digitalis
C. Apomorphine
D. CuSO4
18. Drug with high affinity but no efficacy is also called as………
A. Partial antagonist
B. Agonist
C. Partial agonist
D. Antagonist
19. _______ is the example of non-irritating purgative
A. CMC
B. Anthraquinone
C. Triphenylmethane
D. Ricinolic acid
20. Identify the IUPAC name of naproxen:
A. 2-(6-Ethoxy-2-naphthyl)propanoic acid
B. 2-(6-Methoxy-2-naphthyl)propanoic acid
C. 2-(6-Methoxy-2-naphthyl)propanoic acid
D. -2-(6-Methoxy-1-naphthyl)propanoic acid
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